DCNS | Burton, Jodie - Dept-DCNS-122 ,

Dr. Jodie Burton

MD, MSc, FRCPC

Positions

Clinical Associate Professor

Hotchkiss Brain Institute

Clinical Associate Professor

Cumming School of Medicine, Department of Clinical Neurosciences

Assistant Professor

Cumming School of Medicine, Department of Community Health Sciences

Full Member

Hotchkiss Brain Institute

Contact information

Phone number

office: 4032207572

Location

Academic office: Health Sciences Centre, Area 3,room 1007c

Preferred method of communication

email

Background

Biography

Dr. Burton obtained her BSc in the Life Sciences in 1996 and her MD in 2000 at the University of Toronto.  She then undertook a Neurology residency at the University of Toronto completed in 2005.  At that time she spent two years in a Multiple Sclerosis fellowship with Dr. Paul O'Connor from 2005-2007 as well as obtaining her MSc in Clinical Epidemiology from 2006-2008 (both at the University of Toronto).  She was on staff at the University of Toronto at the MS clinic from 2007-2009 until she joined the Department of Clinical Neurosciences and the MS Program as well as the Department of Community Health Sciences at the University of Calgary in 2009 where she is currently an Associate Clinical Professor and a full member of the MS Research Program with the Hotchkiss Brian Institute.

Dr. Burton's research has focused for over 15 years on the role of vitamin D in MS, most recently in a trial of high-dose vitamin D in the treatment of optic neuritis.  She has also focused on NMOSD and MOG writing many guidelines on the subject as well as escalation strategies for aggressive disease. She is also the co-director of the Autologous Hematopoietic Stem Cell Transplant Program for Multiple Sclerosis at the University of Calgary.  She also participates in the Evidence Based Medicine educational program for neurology residents and supervises students in a variety of research settings.

Projects

A Phase II Trial of High-Dose Vitamin D Induction in Optic Neuritis (VitaDON 2)

A phase II randomized placebo/standard dose controlled treatment trial of high-dose vitamin D in acute optic neuritis to determine if recovery of measures of vision, namely optical coherence tomography metrics, differ based on vitamin D group.  Additional endpoints include conversion to clinically definite MS, texture and advanced MRI measures, and variables associated with vitamin D receptor genes.  


The Role of Autophagy in the Transition to Progressive Multiple Sclerosis

A pilot study of markers of autophagy in secondary progressive MS patients vs relapsing remitting patients to determine if autophagy may be a marker of progression.  Co-investigator with Dr. Shalina Ousman.


A Registry-Based Evaluation of Neuromyelitis Optica Spectrum Disorder and MOG Associated Disease in Alberta, Canada

A planned registry of NMOSD/MOGAD based out of Alberta-based MS clinics.


Aquaporin-4 and Myelin Oligodendrocyte Glycoprotein Antibody Testing in Calgary, Canada

A resident-based (Dr. Jonathan Krett) quality improvement project to determine the rates of duplicate testing of AQP4/MOG at outside centres after local testing in Calgary, the concordance/discordance rates, and associated utility/benefit/costs.  The project will determine under what conditions such testing might be indicated, with the goals of improving resource utilization, costs, and patient care.

Awards

  • Annual Clinical Researcher Award (clinical, adjunct and research faculty), Cumming Medical School, University of Calgary, University of Calgary. 2019
  • Distinguished Reviewer of the Year, Canadian Journal of Neurological Sciences, CNSF. 2014
  • Charcot Young Investigator of 2010 Award, European Charcot Foundation , European Charcot Foundation. 2010