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Bruce Pike




Cumming School of Medicine, Department of Radiology


Cumming School of Medicine, Department of Clinical Neurosciences


Cumming School of Medicine, Department of Radiology | Image Science

Campus Alberta Innovates Chair

Healthy Brain Aging

Full Member

Hotchkiss Brain Institute

Contact information

Phone number

Office: +1 (403) 220-4026


Educational Background

BEng Memorial University,

MEng McGill University,

PhD McGill University,

Postdoc Stanford University,


The focus of my research has been the development and application of quantitative structural and functional magnetic resonance imaging (MRI) methods for basic and clinical neuroscience. I have held major leadership roles in brain imaging research programs, such as Director of the McConnell Brain Imaging Centre of the Montreal Neurological Institute of McGill University and Head of Image Science at the University of Calgary. During the past few years I have also established a new research program at the University of Calgary in the area of MR guided focused ultrasound (FUS) that uses this technology for neurosurgery, drug deliver via FUS-mediated BBB opening, and low intensity pulsed FUS for neuomodulation.  


Areas of Research

Dementia & Cognitive Disorders
Mental Health
Movement Disorders
Multiple Sclerosis
Magnetic Resonance Imaging
Cerebral Blood Flow

Bruce Pike, PhD is the CAIP Chair in Healthy Brain Aging and Head of the Division of Image Science in the Department of Radiology.  He is also a Professor of Clinical Neurosciences and member of the Hotchkiss Brain Institute. Prior to his arrival in Calgary, Dr. Pike was the Killam Professor of Neurology at McGill and Director of the McConnell Brain Imaging Centre of the Montreal Neurological Institute.  Dr. Pike obtained his Ph.D. at McGill University and conducted postdoctoral studies in Radiological Sciences at Stanford University.

Pike investigates magnetic resonance imaging (MRI) methods and applications for basic and clinical neuroscience research.  His recent research has focused on quantitative MRI techniques for measuring tissue microstructure and physiology. He has used his methods to demonstrate focal pathology in multiple sclerosis patients that antedate the development of conventional MRI visible lesions by up to two years.  He has also performed pioneering studies on the relationship between cerebral blood flow and oxygen metabolism in the cortex over a broad range of activation and inhibition conditions in healthy subjects and patients. During the past few years he has launched the MR-guided Focused Ultrasound program at the University of Calgary, which consists of three braod research themes: neurosurgery, drug deliver, and neuromodulation. Dr. Pike has published more than 350 scientific papers and book chapters, is a Senior Editor of the journal NeuroImage, and serves on the advisory board for numerous national and international programs.