Acquired Brain Injury

This Journal Club covers current literature with translatable or clinical applications in acquired brain injury, with topics covering cellular/systems neuroscience, animal modeling, imaging and other detection modalities, neuropsychological and clinical outcomes. Presenters (2 per session) can either delve in depth into one article or compare multiple articles (cell/systems to clinical).

Last Wednesday of each month at 4-5:30pm


Held on Zoom

Advanced Neuroscience Techniques

This journal club will be focusing on introducing and detailing advanced, cutting-edge techniques, tools and technologies that are being implemented in a broad range of neuroscience research focuses. Each session will involve a presentation from 1-3 students covering a topic that is applying cutting edge-technique(s) to a branch of neuroscience research. Topics include, but are not limited to: deep brain, high resolution imaging (multiphoton, etc.); population imaging in freely behaving animals (head-fixed miniscopes, etc.); in vivo electrophysiology; brain connectomics (CLARITY, iDISCO, stacked electron microscopy, etc.); genetic manipulations (CRISPR, Cre-recombinase, etc.); optogenetics and alternatives (non-opsin based optogenetic tools, DREADDs, etc.); single cell RNA sequencing and proteonomics; flow cytometry and fluorescence assisted cell sorting (FACS).

Last Monday of every month, 3-4:30

 

Held on Zoom

Channels, Synapses & Circuits

The focus of this Journal Club is to critically dissect novel (and/or seminal) original research articles that fall within the over-arching fields of ion channel/synaptic physiology; from the level of basic synaptic transmission and channel biophysics to the functional consequences on neural circuits and behaviour. The papers we discuss commonly employ distinct techniques that include, but are not limited to, electrophysiology (patch clamp), laser-scan imaging, molecular biology, optogenetic manipulations, and behavioural assays. We do not restrict papers based on the research topic (for example, learning & memory, addiction, stress, neuropathology) or model systems, but rather that the research questions must involve interrogation of ion channel function and/or the synapse. 

Alternating Fridays at 9:30-10:30am

 

Held on Zoom

Developmental Neuroimaging

The Developmental Neuroimaging Journal Club focuses on the healthy development of the human brain, developmental disorders, and intervention studies conducted using neuroimaging techniques in a pediatric population. Our journal club emphasizes the use of neuroimaging to produce an understanding of developmental trajectories and how changes in the brain may underlie important topics in mental health.

Alternating Wednesdays 11am - 12pm

 

Held on Zoom

Developmental Neuroscience

This Journal Club reviews current literature in the field of developmental neuroscience. Emphasis is placed on fundamental, cutting-edge discoveries and technologies that have significant impact on enhancing our understanding of the mechanisms that control development of neural tissues and cells.

Alternating Thursdays at 12-1pm

 

Held on Zoom

Functional and Structural MRI

This Journal Club encourages presentations of recent articles incorporating the use of magnetic resonance imaging (MRI) towards broader research goals.  Topics are chosen by the presenter, and may cover articles covering a range of topics including brain physiology, MRI physics, multi-modal imaging, resting- and task-based fMRI, and use of MRI as a tool of clinical research into neurologic and psychiatric conditions.  Applied MRI topics aside from neuroscience are welcome.

Under current Covid restrictions and uncertainty, meetings will be held via Zoom (details to come), although the HBA conference room (HSC-2903, Foothills) is booked for the fall term out of optimism.  Please contact Conrad for more information.

Meetings are scheduled every second Thursday at 11am.

Healthy Brain Aging

What happens to the brain as we age? What biomarkers, models and interventions have we developed? How can we understand and support a person living with dementia? This Journal Club reviews current literature and emerging techniques related to cognitive decline in aging as well as the diagnosis, prevention and treatment of dementia. Topics include, but are not limited to: mechanisms of neurovascular (un)coupling in aging; clinical biomarkers for early detection of dementia; cutting-edge animal and computational models; exercise and cognitive/behavioral interventions for amelioration/prevention of symptoms. Each session will focus on a core topic, and will consist of three presentations (physiology-focused; behavioral/social-focused; 3-minute investor pitch) followed by a facilitated discussion with the aim of dissecting and contextualizing presentation content. This is a great opportunity for basic and clinical researchers to: improve your understanding of the mechanisms, diagnosis and implications of neural and vascular dysregulation/degeneration in aging; develop critical analysis and strategic communication skills; connect/network with colleagues within this emerging cross-disciplinary field of neuroscience.

Third Wednesday of the month starting September 19th, 12-2 pm

 

Held on Zoom

Multiple Sclerosis

This Journal Club reviews inspiring pieces of work. The range of acceptable topics is broad (e.g. axon regeneration, biomarkers, demyelination/remyelination, genetics, immunology, stem cells, clinical trials, etc.) but there must be a clear connection to multiple sclerosis research. This journal club will be open to MS-interested trainees, clinicians and researchers from UofC, UofA, UofL and MRU. Each week two research groups will participate in presenting the paper. A lead presenter from one of the research groups will select the article and assign figures to participants.

Second/Third Friday of the month at 3-4pm 

 

Held on Zoom

Non-invasive Neurostimulation

This Journal Club is about non-invasive neurostimulation (hosted by the N3 network).  N3 investigators use Transcranial Magnetic Stimulation (TMS) to non-invasively stimulate small targeted regions of the brain with applications in research related to: movement disorders, mental health, cerebral palsy and neurodevelopmental disorders, neurorehabilitation, pediatric traumatic brain injury and concussion, pain and neuromuscular fatigue.

Please e-mail the organizer for date confirmation.

 

Held on Zoom

Neural Systems & Behaviour

This Journal Club reviews current literature in the field of behavioural neuroscience and neuroethology at a systems level. Emphasis will be placed on examination of work employing novel, cutting-edge methods to better understand the how circuits in the nervous system interact to control a number of behaviours in a variety of model and non-model organisms; including, cognitive (ie. Memory and learning, reward and feeding, stress, etc.), motor (ie. Voluntary movement, prehension, locomotion, respiration, etc.), sensory (ie. Somatosensory, pain, vision, hearing, olfaction, etc.), neural injury & repair, and autonomic topics.

Alternating Fridays at noon-1:00pm

 

Held on Zoom

Science Writing

We cover a wide variety of topics to help improve your science writing abilities. Every session we have fun presentations, workshops, and more...

This year we will be focussing on lay abstracts, grant applications, article writing, pop science writing, social media, and many others!

We are excited to welcome speakers from other faculties and programs as well. Among those speakers include science communicator Jay Ingram as well as Sarah Hewitt.

Alternating Fridays at 1:00pm

 

Held on Zoom

Stroke Imaging

Our meetings fluctuate between journal clubs and Imaging/project meetings. We try to have 1 journal club and around 2-3 project updates meetings per month. Our projects and meetings focus on studying imaging techniques to assess thrombus characteristics, leptomeningeal collaterals and tissue perfusion in patients with major acute ischemic stroke using CTA, dynamic CTA and perfusion CT. Our main trials seek to understand thrombus characteristics on imaging that can predict recanalization with thrombolytics in patients with acute ischemic stroke, as well as to understand the additional clinical utility of perfusion CT and multiphase CTA when compared to CT brain and conventional CT-angio. 

 Wednesdays at 3:00-4:00pm

 

Held on Zoom

Translational Research and Precision Medicine

This Journal Club covers basic science, clinical research, and patient perspectives, and aims to be a forum for discussing translational research and precision medicine. It serves a wide array of researchers and clinicians and covers breadth and depth in the field of neuroscience. Translational research and precision medicine are topics that are becoming increasingly prominent and important in science and medicine, since they bridge the gap between basic science research, clinical applications, and personalized medicine/patient satisfaction. Although each area of research attacks scientific questions and health problems from a different perspective, they all inherently connect to the same overarching questions and end-goals for finding health solutions and serving patients. Thus, our journal club facilitates the translation of research from bench-side to bedside to bridge gaps in knowledge. This translation doesn’t just stop at bedside treatment, as patients' perspectives and experiences will also be featured here.

How our Journal Club works: Every month, we will host a two hour session revolving around a specific neurological disease or mental illness. Each session will feature basic science and clinical research on that topic by having presenters discuss one paper from each perspective. Additionally, we will also feature a patient guest speaker to speak about their perspective and experiences with that illness. This will be a great opportunity for everyone to understand these illnesses from a broader perspective, and learn about cellular, molecular and clinical applications, keeping precision medicine and patient needs in mind.

First Thursday of the month at 12-2pm 

 

Held on Zoom

Undergraduate Neuroscience

This journal club is a neuroscience-themed club for undergraduate summer students affiliated with the Hotchkiss Brain Institute. As neuroscience undergraduates come from vastly different neuroscience fields, we will not restrict our journal club to a specific topic or perspective in neuroscience. Instead, presenters will choose and present any neuroscience journal article they like (or dislike). We have three goals: 1) develop critical thinking skills in undergraduate students; 2) expose undergraduate students to the techniques, approaches, and ideas used in a variety of neuroscience fields; and 3) create a better community for HBI summer students by giving students weekly opportunities to meet. For more details, join our group on Facebook. https://www.facebook.com/groups/490735347924413/

Fridays at 11-12pm

 

Held on Zoom