Single Cell Platforms

Single Cell Platforms

Single-cell transcriptomics is a powerful technology that allows researchers to measure gene expression at the resolution of individual cells. Unlike traditional bulk RNA sequencing, which averages signals across thousands or millions of cells, single-cell methods capture the unique molecular profile of each cell. This makes it possible to identify rare cell populations, discover new cell types, study cellular heterogeneity, and understand how individual cells change in response to development, environment, or disease.

We provide guidance on generating high-viability single-cell suspensions from CNS (and other tissues) for transcriptomic studies. Our team helps optimize tissue dissociation protocols, ensuring samples are ready for high-quality, reproducible single-cell transcriptomics workflows.

We currently offer library preparation services using 10x Genomics and Parse Biosciences platforms.

chromium

10x Genomics Chromium system library preparation services:

  • 10x 3' single cell and nucleus gene expression
  • 10x 5' gene expression
  • 10x 3' on-chip multiplexing
  • 10x Flex Gene Expression – profiling of fixed cells
  • 10x Single cell ATAC-seq 
  • 10x multiomics – combining gene and protein expression or gene expression and ATAC profiling 

Parse Biosciences Evercode Platform:

This split-pool combinatorial barcoding technology enables the processing of fixed cells and allows for highly scalable studies involving hundreds of thousands of cells across multiple conditions.