Zelma Kiss


Clinical Neurosciences

Full Member

Hotchkiss Brain Institute

M.D. (Doctor of Medicine)

Ph.D. (Doctor of Philosophy)


Contact information


Office: 403.220.4839
Clinic: 403.944.8602

Web presence



Office : HRIC1AC58

Preferred method of communication

Administrative Assistant: 
Sue Nelson
3280 Hospital Dr. NW
Calgary, AB  T2N 4N1
P: 403-220-5572
E: nelsons@ucalgary.ca

Clinical/Patient inquires:
Madeline Garcia
P: 403.944.8602

For MRgFUS for Essential Tremors (HIFU) please contact:
Salimah Jetha
E: hifu@ucalgary.ca

Research and teaching

Research areas

  • Mental Health
  • Movement Disorders
  • Spinal Cord/Never Injury & Pain
  • electrophysiology
  • neuromodulation
  • optical imaging
  • biomedical imaging
  • biomedical engineering
  • neural prostheses
  • depression
  • pain

Research activities

Dr. Kiss’s research aims have focused on the mechanisms of action of deep brain stimulation (DBS). DBS is a neural prosthesis that modulates specific brain nuclei and pathways to restore or improve movement disorders such as Parkinson disease, dystonia and tremor. Her lab uses slice electrophysiology, behaviour, optical imaging, and immunohistochemistry in rodents to unravel how DBS works, in parallel to studies in humans who have DBS surgery. She collaborates with colleagues in biomedical engineering (Dr. Murari) to develop chronic models of DBS in rodents and veterinarian medicine (Dr. Whelan) to develop new targets for DBS. Recent research has extended to the development of neural prostheses to restore somatosensory function, psychiatric indications such as depression, and new neuromodulation therapies for pain.

In addition, Dr. Kiss is a functional & stereotactic neurosurgeon treating movement disorders, psychiatric conditions, epilepsy and pain, including trigeminal neuralgia and headache. She directs the Neuromodulation Program for Alberta Health Services Calgary, and is co-director of the MR Guided Focused Ultrasound Program.