Minh Dang Nguyen
Research and teaching
- Dementia & Cognitive Disorders
My research program aims to understand the basic mechanisms governing neurodegenerative disorders. We study the cytoskeleton i.e. the internal scaffolding that provides structure for the cell, transports materials and sends signals across the cell. Mutations or alterations in this dynamic framework or its regulatory proteins can lead to neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis. In parallel, we investigate the physiological functions of the cytoskeleton during brain development, maturation and plasticity with the ultimate goal to harness its biology for neuroprotection and neurorepair (for further details, see Philosophy of Research).