Alvin Joselin

Research Assistant Professor

Clinical Neurosciences

Associate Member

Hotchkiss Brain Institute

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Northwestern University

PhD Molecular Biology

University of Düsseldorf

MSc Microbiology

Bharathidasan University

BSc Microbiology

University of Madras

Contact information

Location

Office : HRIC1A32

Research and teaching

Research areas

  • Genetic causes of Parkinson’s Disease
  • Molecular mechanisms in PD

Research activities

My current research centers around understanding the death pathways that control neurodegeneration in  Parkinson's disease and the mechanisms and function of PD linked genes. I have been involved in studies that define the pathways important in neuronal death using animal models. My current research focuses on the intersection of mitochondrial dynamics, endoplasmic reticulum (ER) stress and their implications on neurodegeneration via regulation of cell death pathways or activation of neuro-immunological responses. I use a combination of multi-disciplinary approaches to answer these specific questions with a goal to not just understand the basic mechanisms in PD pathogenesis but also to apply the knowledge gained from these studies for the benefit of those afflicted with this neurodegenerative condition.


Publications

PubMed