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HBI - Melbourne Epilepsy Symposium

May 1 - 2, 2017

Clara Christie Theatre, Health Sciences Centre

Foothills Campus, University of Calgary

RSVP HERE by April 21, 2017

Questions directed to

Bios for speakers can be downloaded here

The Hotchkiss Brain Institute, the Melbourne Neuroscience Institute at the University of Melbourne, and the Florey Institute of Neuroscience and Mental Health invite you to the HBI - Melbourne Epilepsy Symposium. Featuring presentations from the Brain and Mental Health Epilepsy NeuroTeam and Melbourne researchers to promote collaborations in epilepsy-related research.

Epilepsy is one of nine NeuroTeams within the University of Calgary Brain and Mental Health research strategy. Led by the Hotchkiss Brain Institute, the Brain and Mental Health research strategy provides a unifying direction for brain and mental health research at the University of Calgary, positioning researchers to unlock new discoveries and treatments for brain health in our community by working in interdisciplinary teams.


Monday, May 1

8:00 – 9:00 am: Symposium Registration, Full Breakfast

9:00 – 9:15 am: Welcome and Introductions

Session 1 - Imaging

9:15 – 9:30 am: “Fixel Based Analysis: Investigating White Matter Fibre Density and Morphology”Alan Connelly (Florey)

9:30 – 9:45 am: “Spike Wave EpilepsiesGraeme Jackson (Florey)

9:45 – 10:00 am: “Human Epilepsy Imaging at the Seaman Centre”Richard Frayne (HBI)

10:00 – 10:15 am: “On the Reliability of Scalp EEG-fMRI Studies of Epilepsy: The significance of missing epileptogenic spikes in human markup”Amir Omidvarnia (Florey)

10:30 – 10:45 am: Tea/Coffee break

10:45 – 11:00 am: "More Than One Type of Black Dog in Epilepsy: Phenotypes of Depression", Genevieve Rayner (Florey)

11:00 – 11:15 am: “Novel MRI and CT Approaches to Study of Human Focal Epilepsy”, Paolo Federico (HBI)

11:15 – 11:30 am: "Doing More With Less: single-shell 3-tissue constrained spherical deconvolution", Thijs Dhollander (Florey)

11:30 – 11:45 am: “Improving the Characterization of the Pre-Ictal State by Quantifying the Variability of Functional Connection Strength”, Bradley Goodyear (HBI)

11:45 am – 12:30 pm: Questions/Discussion

12:30 – 1:30 pm: Lunch

Session 2 – Pathomechanisms, Mouse Models, Genetics, TBI

1:30 – 1:45 pm: “Postictal Hypoxia: Phenomenon, Mechanism, Treatment and Implications”, Cam Teskey (HBI)

1:45 – 2:00 pm: “Using a Spider Toxin to Treat Dravet Syndrome”, Steve Petrou (Florey)

2:00 – 2:15 pm: “Metabolic Mechanisms of Functional Neuroprotection in Epilepsy and Autism Spectrum Disorder”, Jong Rho (HBI)

2:15 – 2:30 pm: “Targeted Therapies for KCNT1 Epilepsies”, Melody Li (Florey)

2:30 – 2:45 pm: "Using Zebrafish and Mouse Models of Epilepsy for Anti-Seizure Drug Development”, Deborah Kurrasch (HBI)

2:45 – 3:00 pm: Tea/Coffee Break

3:00 – 3:15 pm: “Zinc and Febrile Seizures”, Christopher Alan Reid (Florey)

3:15 – 3:30 pm: “The Cytoskeleton in Epilepsy: Cause, Consequence or Bystander?“, Minh Dang Nguyen (HBI)

3:30 – 3:45 pm: "Novel Therapies for Acquired Epilepsy", Sandy Shultz (MNI)

3:45 – 4:00 pm: “Epigenetic Change and Post-Traumatic Epilepsy”, Richelle Mychasiuk (HBI)

4:00 – 4:15 pm: “Somatic Mutations in Sporadic Epilepsies”, Michael Hildebrand (MNI)

4:15 – 5:00 pm: Questions/Discussion

5:00 – 6:30 pm:  Symposium Social – registered attendees

Tuesday, May 2

8:00 – 9:00 am: Full Breakfast

9:00 – 9:15 am: Welcome to Day 2

Session 3 – Neural/Silicone Interface, Mathematics

9:15 – 9:30 am: “Playing the Long Game - insights from 24/7 neurophysiology”, Dean Freestone (MNI)

9:30 – 9:45 am: “Miniaturized Engineering Opportunities in Neuroscience”, Colin Dalton (HBI)

9:45 – 10:00 am: Towards a Patient-Specific Network Characterization of Epileptogenesis”, Andre Peterson (MNI)

10:00 – 10:15 am: “Correlation Dynamics in Epileptic Seizure Problems and Brain Network Structures: Post-ictal Signatures”, Kris Vasudevan (HBI)

10:15 – 10:45 pm: Questions/Discussion

10:45 – 11:00 am: Tea/Coffee break

Session 4 – Epidemiology

11:00 – 11:15 am: “Linked Electronic Medical Records as a Means of Studying the Epidemiology of Epilepsy”, Colin Josephson (HBI)

11:15 – 11:30 am: "Heart Rate Variability: A Biomarker of SUDEP Risk?", Ken Myers (MNI)

11:30 – 11:45 am: “The Data Science Center Initiative”, Samuel Wiebe (HBI)

11:45 – 12:00 pm: “The Epidemiology and Aetiologies of Severe Epilepsies of Infancy”, Katherine Howell (MNI)

12:00 pm – 12:30 pm: Questions/Discussion

12:30 – 1:30 pm: Lunch

Symposium Academic Leads

Dr. Michael Hildebrand – Michael Hildebrand is a neurogeneticist at the Melbourne Neuroscience Institute, University of Melbourne and heads the Translational Neurogenetics Laboratory in the Epilepsy Research Centre at the Melbourne Brain Centre, Australia.

Dr. Nathalie Jetté - Nathalie Jetté is a Professor in Neurology and Community Health Sciences, Director of the Epilepsy Clinic and Seizure Monitoring Unit, Leader of the Hotchkiss Brain Institute (HBI) Epilepsy NeuroTeam and Leader of the HBI Neuro and Mental Health Research Clinic at the University of Calgary.

Dr. Christopher Alan Reid - Chris Reid is a Dowd Fellow and heads the Neurophysiology of excitable networks laboratory at the Florey Institute of Neuroscience and Mental Health, Melbourne Australia.

Dr. G. Cam Teskey - Cam Teskey is a Professor in Cell Biology and Anatomy, Education Director for the Hotchkiss Brain Institute and Co-Leader of the Hotchkiss Brain Institute (HBI) Epilepsy NeuroTeam. He is the representative from the Canadian Research Initiative to the Canadian League Against Epilepsy (CLAE) and sits on the CLAE Education Committee.