The Hotchkiss Brain Institute
Healthy Brains for Better Lives
Professor, University of Calgary
HBI Education Director
Office: HSC 2103 Lab: HSC 2046
3330 Hospital Drive N.W Calgary, AB T2N 4N1
My research program focuses on three independent but related fields of research that have both basic (curiosity driven) and applied (health sciences) aspects to them:
My work uses animal models of diseases, syndromes and treatments. I measure animal behaviour using a variety of assessment techniques (e.g. open field, single pellet reaching task, pasta matrix task, elevated plus maze, cylinder task, and ladder task). I also use behavioural experience (skilled-reaching, wheel running, enriched environments) to understand how the brain changes. I employ electrophysiological (Intracortical microstimulation, EEG, evoked potentials, multi- and single-unit activity), and pharmacological (systemic and focal infusions) techniques to elucidate the underlying mechanisms. In collaboration with a number of colleagues I have also examined alterations in neural and glial cell anatomy at the cellular, ultrastructural and molecular/genetic levels.